Use this url to cite ETD: https://hdl.handle.net/20.500.12259/115718
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3,6-diariliden-2,5-piperazindiono sintezė ir savybės
Field of Science
Chemija / Chemistry (N003)
Type of publication
type::text::thesis::master thesis
Title
3,6-diariliden-2,5-piperazindiono sintezė ir savybės
Other Title
3,6-diarilidene-2,5-piperazindione Sinthesys and properties
Author
Chalkovskaja, Renata |
Advisor
Extent
108 p.
Date Issued
2006-06-15
Abstract
In this work the aldol condensation reactions of 2,5-piperazinediones with carbonyl compounds were investigated. It was found that condensation of title compounds in the system CH3COONa/(CH3CO)2O yielded 3,6-bis(arylidene)-2,5-piperazinediones. These compounds could be easily converted to α-amino acid by reducing with zinc powder and hydrolyzing with concentrated acid or Ba(OH)2 solution. Interaction of 1,4-dibenzyl-2,5-piperazinedione with 4- substituted benzaldehydes does not lead to the formation of the benzylidene derivative because of steric hindrance of N-benzyl groups. The effect of different reaction conditions were studied. The purity of the obtained compounds was controlled by thin layer chromatography. The structure was proved by the data 1H NMR and IR spectra.
Language
Lietuvių / Lithuanian (lt)
Defended
Taip / Yes
Access Rights
Atviroji prieiga / Open Access